Introduction: The Rhesus (Rh) antigen is the most polymorphic of human blood group systems second only to the ABO in transfusion and transplantation medicine with significance in iso-immunization which can cause haemolytic disease of the foetus and newborn. This study was carried out to determine the prevalence of Rhesus negativity amongst antenatal clinic attendees in the University of Uyo Teaching Hospital. Methodology: This was a 5-year retrospective study carried out between March 1st, 2012 and February 28th, 2017. Data containing the ABO and Rhesus blood group of all antenatal clinic attendees was collected from the Laboratory registers and analysed using Microsoft excel. Results: The prevalence rate of Rhesus D negative women was 4.40%. The average yearly attendance was 2861 women. The commonest blood group was O with 8232 (57.54%), followed by blood group A, 3416 (23.88%) and blood group B, 2388 (16.69%) while the least common blood group was AB, 271 (1.89%). Most Rhesus D-negative women were of blood group O; 382 (60.78%), followed by group A; 142 (22.58%), and blood group B was 94 (14.49%). AB blood group was the least; 11 (1.70%). Sensitization rate among the 629 Rhesus D-negative women was 1.11%. Conclusion: The prevalence of rhesus negativity is low in the population studied with an ABO distribution that mirrored the antenatal population, hence the overall need for immunoprophylaxis. It is however very necessary to educate and counsel all non-sensitized Rhesus negative women on the need for antenatal and post-partum immuno-prophylaxis as well as public enlightenment on the rationale for Rhesus typing, especially among women.
| Published in | Clinical Medicine Research (Volume 10, Issue 1) |
| DOI | 10.11648/j.cmr.20211001.15 |
| Page(s) | 26-30 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Blood Group, Rhesus, Pregnancy, Haemolytic Disease
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APA Style
Emem Abasi Bassey, Matthias Gabriel Abah, Christopher Azubuike Opone, Aniekan Linus Jackson. (2021). Prevalence of Rhesus Negative Status Amongst Antenatal Atendees in the University of Uyo Teaching Hospital, Uyo, Nigeria: A 5-Year Review. Clinical Medicine Research, 10(1), 26-30. https://doi.org/10.11648/j.cmr.20211001.15
ACS Style
Emem Abasi Bassey; Matthias Gabriel Abah; Christopher Azubuike Opone; Aniekan Linus Jackson. Prevalence of Rhesus Negative Status Amongst Antenatal Atendees in the University of Uyo Teaching Hospital, Uyo, Nigeria: A 5-Year Review. Clin. Med. Res. 2021, 10(1), 26-30. doi: 10.11648/j.cmr.20211001.15
AMA Style
Emem Abasi Bassey, Matthias Gabriel Abah, Christopher Azubuike Opone, Aniekan Linus Jackson. Prevalence of Rhesus Negative Status Amongst Antenatal Atendees in the University of Uyo Teaching Hospital, Uyo, Nigeria: A 5-Year Review. Clin Med Res. 2021;10(1):26-30. doi: 10.11648/j.cmr.20211001.15
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Download@article{10.11648/j.cmr.20211001.15,
author = {Emem Abasi Bassey and Matthias Gabriel Abah and Christopher Azubuike Opone and Aniekan Linus Jackson},
title = {Prevalence of Rhesus Negative Status Amongst Antenatal Atendees in the University of Uyo Teaching Hospital, Uyo, Nigeria: A 5-Year Review},
journal = {Clinical Medicine Research},
volume = {10},
number = {1},
pages = {26-30},
doi = {10.11648/j.cmr.20211001.15},
url = {https://doi.org/10.11648/j.cmr.20211001.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20211001.15},
abstract = {Introduction: The Rhesus (Rh) antigen is the most polymorphic of human blood group systems second only to the ABO in transfusion and transplantation medicine with significance in iso-immunization which can cause haemolytic disease of the foetus and newborn. This study was carried out to determine the prevalence of Rhesus negativity amongst antenatal clinic attendees in the University of Uyo Teaching Hospital. Methodology: This was a 5-year retrospective study carried out between March 1st, 2012 and February 28th, 2017. Data containing the ABO and Rhesus blood group of all antenatal clinic attendees was collected from the Laboratory registers and analysed using Microsoft excel. Results: The prevalence rate of Rhesus D negative women was 4.40%. The average yearly attendance was 2861 women. The commonest blood group was O with 8232 (57.54%), followed by blood group A, 3416 (23.88%) and blood group B, 2388 (16.69%) while the least common blood group was AB, 271 (1.89%). Most Rhesus D-negative women were of blood group O; 382 (60.78%), followed by group A; 142 (22.58%), and blood group B was 94 (14.49%). AB blood group was the least; 11 (1.70%). Sensitization rate among the 629 Rhesus D-negative women was 1.11%. Conclusion: The prevalence of rhesus negativity is low in the population studied with an ABO distribution that mirrored the antenatal population, hence the overall need for immunoprophylaxis. It is however very necessary to educate and counsel all non-sensitized Rhesus negative women on the need for antenatal and post-partum immuno-prophylaxis as well as public enlightenment on the rationale for Rhesus typing, especially among women.},
year = {2021}
}
TY - JOUR T1 - Prevalence of Rhesus Negative Status Amongst Antenatal Atendees in the University of Uyo Teaching Hospital, Uyo, Nigeria: A 5-Year Review AU - Emem Abasi Bassey AU - Matthias Gabriel Abah AU - Christopher Azubuike Opone AU - Aniekan Linus Jackson Y1 - 2021/02/09 PY - 2021 N1 - https://doi.org/10.11648/j.cmr.20211001.15 DO - 10.11648/j.cmr.20211001.15 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 26 EP - 30 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20211001.15 AB - Introduction: The Rhesus (Rh) antigen is the most polymorphic of human blood group systems second only to the ABO in transfusion and transplantation medicine with significance in iso-immunization which can cause haemolytic disease of the foetus and newborn. This study was carried out to determine the prevalence of Rhesus negativity amongst antenatal clinic attendees in the University of Uyo Teaching Hospital. Methodology: This was a 5-year retrospective study carried out between March 1st, 2012 and February 28th, 2017. Data containing the ABO and Rhesus blood group of all antenatal clinic attendees was collected from the Laboratory registers and analysed using Microsoft excel. Results: The prevalence rate of Rhesus D negative women was 4.40%. The average yearly attendance was 2861 women. The commonest blood group was O with 8232 (57.54%), followed by blood group A, 3416 (23.88%) and blood group B, 2388 (16.69%) while the least common blood group was AB, 271 (1.89%). Most Rhesus D-negative women were of blood group O; 382 (60.78%), followed by group A; 142 (22.58%), and blood group B was 94 (14.49%). AB blood group was the least; 11 (1.70%). Sensitization rate among the 629 Rhesus D-negative women was 1.11%. Conclusion: The prevalence of rhesus negativity is low in the population studied with an ABO distribution that mirrored the antenatal population, hence the overall need for immunoprophylaxis. It is however very necessary to educate and counsel all non-sensitized Rhesus negative women on the need for antenatal and post-partum immuno-prophylaxis as well as public enlightenment on the rationale for Rhesus typing, especially among women. VL - 10 IS - 1 ER -
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