@article{10.11648/j.ejpm.20210905.14,
  author = {Sanjoy Kumar Saha and Md. Nuruzzaman and Sajalendu Biswas and Amitav Saha and Mohammad Obayedur Rahman and Mohammad Asaduzzaman},
  title = {Assessment of COVID-19 Cases by Haematological and Biochemical Markers: A Tertiary Care Hospital Study in Dhaka, Bangladesh},
  journal = {European Journal of Preventive Medicine},
  volume = {9},
  number = {5},
  pages = {133-139},
  doi = {10.11648/j.ejpm.20210905.14},
  url = {https://doi.org/10.11648/j.ejpm.20210905.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20210905.14},
  abstract = {Background: On 8 March 2020 the first COVID-19 case was detected in Bangladesh. Day by day this disease is changing its own nature and dimension. So, it is very difficult to define the exact risk factors associated with such ferocious diseases. In this situation, haematological and biochemical analysis of COVID-19 patients may play an important role in the current and future planning of COVID treatment. Aim of the study: The aim of this study was to assess the COVID-19 status of Covid patients by haematological and biochemical markers. Materials and Methods: This prospective observational study was conducted among 350 participants who attended the Bashundhara Ad-Din Medical College Hospital, Hasnabad, South Keranigonj, Dhaka, Bangladesh after confirmation by RT-PCR. Using 5 ml fasting venous blood samples different haematological and biochemical biomarkers were analyzed. These were analyzed in auto analysis using a standard protocol as per the manufacturer’s instructions. Finally, results were analyzed using standard statistical calculation by% positivity, confidence interval, p values where p≤0.05 was considered as statistically significant. Results: In this study, in critical participant group, the mean (±SD) HBC, RBC, TLC, PCV, NLR, Platelet Counts, SGOT and SGPT were found 11.56±2.07, 3.64±2.82, 12372±2920, 29.17±7.84, 2.8±0.32, 98743±32127, 67.91±31.54 and 71.39±33.74 respectively. On the other hand, in non-critical patient group those reading were found 12.78±2.17, 4.02±2.90, 10956±2744, 35.03±8.22, 2.7±0.28, 129544±51228, 65.68±27.96 and 67.55±26.57 respectively. In analyzing the haematological and biochemical parameters among participants we found ‘extremely significant correlations’ between critical and non-critical groups in HBC, TLC, PCV, Platelet Counts, S. Creatinine and D-Dimer test results where p values were Conclusion: Haematological and biochemical markers may be considered as the most potential parameters in assessing the severity of COVID-19 infection. But, advanced training required for laboratory personnel’s who are responsible for collecting, transporting and handling biological samples and carrying out the various laboratory tests for patients with COVID-19 is recommended.},
 year = {2021}
}

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TY  - JOUR
T1  - Assessment of COVID-19 Cases by Haematological and Biochemical Markers: A Tertiary Care Hospital Study in Dhaka, Bangladesh
AU  - Sanjoy Kumar Saha
AU  - Md. Nuruzzaman
AU  - Sajalendu Biswas
AU  - Amitav Saha
AU  - Mohammad Obayedur Rahman
AU  - Mohammad Asaduzzaman
Y1  - 2021/10/29
PY  - 2021
N1  - https://doi.org/10.11648/j.ejpm.20210905.14
DO  - 10.11648/j.ejpm.20210905.14
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 133
EP  - 139
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20210905.14
AB  - Background: On 8 March 2020 the first COVID-19 case was detected in Bangladesh. Day by day this disease is changing its own nature and dimension. So, it is very difficult to define the exact risk factors associated with such ferocious diseases. In this situation, haematological and biochemical analysis of COVID-19 patients may play an important role in the current and future planning of COVID treatment. Aim of the study: The aim of this study was to assess the COVID-19 status of Covid patients by haematological and biochemical markers. Materials and Methods: This prospective observational study was conducted among 350 participants who attended the Bashundhara Ad-Din Medical College Hospital, Hasnabad, South Keranigonj, Dhaka, Bangladesh after confirmation by RT-PCR. Using 5 ml fasting venous blood samples different haematological and biochemical biomarkers were analyzed. These were analyzed in auto analysis using a standard protocol as per the manufacturer’s instructions. Finally, results were analyzed using standard statistical calculation by% positivity, confidence interval, p values where p≤0.05 was considered as statistically significant. Results: In this study, in critical participant group, the mean (±SD) HBC, RBC, TLC, PCV, NLR, Platelet Counts, SGOT and SGPT were found 11.56±2.07, 3.64±2.82, 12372±2920, 29.17±7.84, 2.8±0.32, 98743±32127, 67.91±31.54 and 71.39±33.74 respectively. On the other hand, in non-critical patient group those reading were found 12.78±2.17, 4.02±2.90, 10956±2744, 35.03±8.22, 2.7±0.28, 129544±51228, 65.68±27.96 and 67.55±26.57 respectively. In analyzing the haematological and biochemical parameters among participants we found ‘extremely significant correlations’ between critical and non-critical groups in HBC, TLC, PCV, Platelet Counts, S. Creatinine and D-Dimer test results where p values were Conclusion: Haematological and biochemical markers may be considered as the most potential parameters in assessing the severity of COVID-19 infection. But, advanced training required for laboratory personnel’s who are responsible for collecting, transporting and handling biological samples and carrying out the various laboratory tests for patients with COVID-19 is recommended.
VL  - 9
IS  - 5
ER  - 

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