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Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia

Received: 2 April 2021     Accepted: 15 April 2021     Published: 31 December 2021
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Abstract

There are currently no vaccines with hundred percent efficacy or no effective treatments for lessening hospitalizations brought about by Coronavirus disease 2019 (COVID-19). The influenza vaccination has proposed as a potential method to decrease the seriousness of COVID-19. A prospective cohort study of 37 individuals of Paediatric, Adult and Geriatric group was taken and they were vaccinated against the influenza virus for two consecutive years with the ‘Influenza’ vaccine. Antibody titers were then measured and PCR tests were done to confirm infections. The severity of infection was reflected by hospitalization and emergency unit admission. Examination was performed to analyze the connection between influenza vaccine status and hospitalization. As compared to those who had been vaccinated, COVID-19-positive patients who had not received influenza vaccine during the previous year had a higher risk of hospitalization and ICU admission. Some individuals who were vaccinated for influenza did not even develop any symptoms at all and the others were noticed to have very faint symptom onset. The findings from this study indicate that influenza vaccination can protect against COVID-19 infection in moderate and severe cases. Regardless of comorbidity, this calming influence remains. The literature indicates that RNA interference and natural killer cell activation could be involved.

Published in European Journal of Preventive Medicine (Volume 9, Issue 6)
DOI 10.11648/j.ejpm.20210906.15
Page(s) 162-167
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

COVID-19, Influenza, Vaccine, Vaccination, Efficacy, Coronavirus

References
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  • APA Style

    Rahul Anil Sethi, Lalit Hasija, Karine Hakobyan, Armine Hakobyan, Sanobar Shariff, et al. (2021). Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia. European Journal of Preventive Medicine, 9(6), 162-167. https://doi.org/10.11648/j.ejpm.20210906.15

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    ACS Style

    Rahul Anil Sethi; Lalit Hasija; Karine Hakobyan; Armine Hakobyan; Sanobar Shariff, et al. Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia. Eur. J. Prev. Med. 2021, 9(6), 162-167. doi: 10.11648/j.ejpm.20210906.15

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    AMA Style

    Rahul Anil Sethi, Lalit Hasija, Karine Hakobyan, Armine Hakobyan, Sanobar Shariff, et al. Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia. Eur J Prev Med. 2021;9(6):162-167. doi: 10.11648/j.ejpm.20210906.15

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  • @article{10.11648/j.ejpm.20210906.15,
      author = {Rahul Anil Sethi and Lalit Hasija and Karine Hakobyan and Armine Hakobyan and Sanobar Shariff and Burhan Kantawala},
      title = {Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia},
      journal = {European Journal of Preventive Medicine},
      volume = {9},
      number = {6},
      pages = {162-167},
      doi = {10.11648/j.ejpm.20210906.15},
      url = {https://doi.org/10.11648/j.ejpm.20210906.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20210906.15},
      abstract = {There are currently no vaccines with hundred percent efficacy or no effective treatments for lessening hospitalizations brought about by Coronavirus disease 2019 (COVID-19). The influenza vaccination has proposed as a potential method to decrease the seriousness of COVID-19. A prospective cohort study of 37 individuals of Paediatric, Adult and Geriatric group was taken and they were vaccinated against the influenza virus for two consecutive years with the ‘Influenza’ vaccine. Antibody titers were then measured and PCR tests were done to confirm infections. The severity of infection was reflected by hospitalization and emergency unit admission. Examination was performed to analyze the connection between influenza vaccine status and hospitalization. As compared to those who had been vaccinated, COVID-19-positive patients who had not received influenza vaccine during the previous year had a higher risk of hospitalization and ICU admission. Some individuals who were vaccinated for influenza did not even develop any symptoms at all and the others were noticed to have very faint symptom onset. The findings from this study indicate that influenza vaccination can protect against COVID-19 infection in moderate and severe cases. Regardless of comorbidity, this calming influence remains. The literature indicates that RNA interference and natural killer cell activation could be involved.},
     year = {2021}
    }
    

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    T1  - Efficacy of Influenza Vaccine on Prophylaxis of COVID-19 – a Prospective Cohort Study Done on 37 Patients in Armenia
    AU  - Rahul Anil Sethi
    AU  - Lalit Hasija
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    AU  - Armine Hakobyan
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    AU  - Burhan Kantawala
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    DO  - 10.11648/j.ejpm.20210906.15
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    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
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    EP  - 167
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20210906.15
    AB  - There are currently no vaccines with hundred percent efficacy or no effective treatments for lessening hospitalizations brought about by Coronavirus disease 2019 (COVID-19). The influenza vaccination has proposed as a potential method to decrease the seriousness of COVID-19. A prospective cohort study of 37 individuals of Paediatric, Adult and Geriatric group was taken and they were vaccinated against the influenza virus for two consecutive years with the ‘Influenza’ vaccine. Antibody titers were then measured and PCR tests were done to confirm infections. The severity of infection was reflected by hospitalization and emergency unit admission. Examination was performed to analyze the connection between influenza vaccine status and hospitalization. As compared to those who had been vaccinated, COVID-19-positive patients who had not received influenza vaccine during the previous year had a higher risk of hospitalization and ICU admission. Some individuals who were vaccinated for influenza did not even develop any symptoms at all and the others were noticed to have very faint symptom onset. The findings from this study indicate that influenza vaccination can protect against COVID-19 infection in moderate and severe cases. Regardless of comorbidity, this calming influence remains. The literature indicates that RNA interference and natural killer cell activation could be involved.
    VL  - 9
    IS  - 6
    ER  - 

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Author Information
  • Department of Operative Surgery and International Affairs, Yerevan State Medical University, Yerevan, Armenia

  • Friends Ent Clinic, Faridabad, Haryana, India

  • Tairov Polyclinic, Etchmiadzin, Armenia

  • Tairov Polyclinic, Etchmiadzin, Armenia

  • Faculty of General Medicine, Yerevan State Medical University, Yerevan, Armenia

  • Faculty of General Medicine, Yerevan State Medical University, Yerevan, Armenia

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