The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy

Hoon Hur; Jie Hoon Kim; Duck Taik Shim; Suk Jin Choi; Pyoung Su Kim; Yu Ri Kim

doi:doi:10.11648/j.js.20210901.13

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The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy

Hoon Hur, Jie Hoon Kim, Duck Taik Shim, Suk Jin Choi, Pyoung Su Kim, Yu Ri Kim

Published in Journal of Surgery (Volume 9, Issue 1)

Received: 30 December 2020 Accepted: 19 January 2021 Published: 25 January 2021

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Abstract

Becker’s nevus, a cutaneous hamartoma, usually occurs as a large, unilateral, hyperpigmented and hypertrichotic patch on the shoulder or upper trunk, which can be present in childhood or adolescence. Becker’s nevus can be treated with traditional laser therapy using various types of lasers including a 532nm potassium titanyl phosphate (KTP) laser, 694nm ruby laser and 755nm alexandrite laser. However, this may cause harmful side effects such as scarring, mottled hypopigmentation, post-inflammatory hyperpigmentation (PIH), purpurae, and crusts. As a result, no standard for the treatment of Becker’s nevus using lasers has been established. Therefore, this study was implemented to investigate the safety and efficacy of treating Becker’s nevus using Dr. Hoon Hur’s Golden Parameter Therapy (GPT) followed by Dr. Hoon Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy (OMS-1 PT) which uses a high fluence 1064nm Q-switched Nd: YAG laser (QSNL). Forty-two Koreans suffering from Becker’s nevus participated in the study and received treatment on a weekly basis for 75-100 sessions using the QSNL according to Dr. Hoon Hur’s GPT then followed by Dr. Hoon Hur’s OMS-1 PT. The parameters for this study were a spot size of 7 mm, a fluence of 2.2 J/cm² and a pulse rate of 10 Hz using a sliding-stacking technique for a single pass over the Becker’s nevus, followed by Dr. Hoon Hur’s OMS-1 PT using a sliding technique for 5 passes with the QSNL over the Becker’s nevus. Upon completion of the last treatment, all 42 patients with Becker’s nevus were cured, having no side effects, and entirely removing the pigmented lesions. None of the 42 patients reported any recurrences after their follow-ups 6-15 months after the final treatment. As a result of this study, we propose therapy to safely and effectively treat Becker’s nevus using a fusion of Dr. Hoon Hur’s GPT and Dr. Hoon Hur’s OMS-1 PT with a high fluence 1064nm QSNL to avoid any recurrences or harmful side effects.

Published in	Journal of Surgery (Volume 9, Issue 1)
DOI	10.11648/j.js.20210901.13
Page(s)	16-21
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Becker’s Nevus, 1064nm Nd: YAG Laser, Dr. Hoon Hur’s GPT, Dr. Hoon Hur OMS-1 PT

References

[1]	Glinick SE, Alper JC, Bogaars H, Brown JA. Becker's melanosis: Associated abnormalities. J Am Acad Dermatol 1983; 9: 509-13.
[2]	Khaitan BK, Dogra D, Manchanda Y, Rathi S. Becker's nevus of the lower limb. Acta Derm Venereol (Stockh) 1998; 78: 238-9.
[3]	AlGhamdi KM, AlKhalifah AI, AlSheikh AM, AlSaif FM. Clinicopathologic profile of Becker's melanosis with atypical features. J Drugs Dermatol 2009; 8: 745-8.
[4]	Kim YJ, Roh MR, Lee JH, Na JI, Ko JY, Jung JM, Lee JH, Chang SE (2018) Clinicopathologic characteristics of early-onset Becker’s nevus in Korean children and adolescents. Int J Dermatol. 57: 55–61.
[5]	Trelles MA, Allones I, Moreno-Arias GA, Vélez M (2005) Becker’s nevus: a comparative study between erbium: YAG and Q-switched neodymium: YAG; clinical and histopathological findings. Br J Dermatol. 152: 308–13.
[6]	Momen S, Mallipeddi R, Al-Niaimi F. The use of lasers in Becker's nevus: An evidence-based review. J Cosmet Laser Ther. August, 2016; 18 (4): 188-192.
[7]	Polder KD, Landau JM, Vergilis-Kalner IJ, Goldberg LH, Friedman PM, Bruce S. Laser eradication of pigmented lesions: a review. Dermatol Surg. 2011; May: 37 (5): 572-95.
[8]	J. R. Person and C. Longcope, “Becker's nevus: an androgen-mediated hyperplasia with increased androgen receptors,” J Am Acad Dermatol. 1984; 10 (2): 235–238.
[9]	Hattori H, Kawashima M, Ichikawa Y, Imokawa G. The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation. J Invest Dermatol. 2004; 122: 1256-1265.
[10]	Okazaki M, Yoshimura K, Suzuki Y. The mechanism of epidermal hyperpigmentation in cafe au lait macules of neurofibromatosis type 1 may be associated with dermal fibroblast- derived stem cell factor and hepatocyte growth factor. Bri J Dermatol. 2003; 148: 689-697.
[11]	Okazaki M, Youshimura K, Uchida G. Epidermal hyperpigmentation in non-syndromic solitary cafe au lait macules may be associated with increased secreation of endothelin-1 by lesional keratinocytes. J Plastic Sur & hand Sur. 2005; 39: 213-217.
[12]	Hur H. The Treatment of Café Au Lait Spot Using Dr. Hoon Hur’s Golden Parameter Therapy. J Dermatol Ther. 2016; 1: 1-4.
[13]	Hur H, Kim YR, Shim DT. The Treatment of Café Au Lait Spot, Partial Unilateral Lentiginosis and Becker's Nevus Using a High Fluence 1064nm Q-swithed Nd: YAG Laser. J Clin and Cosmet Dermatol. 2017; 1: 1-4.
[14]	Baek JO, Park IJ, Lee KR, Ryu HR, Kim JS, Lee SK, Kim YR, Hur H. High-fluence 1064-nm Q-Switched Nd: YAG laser: Safe and effective treatment of café-au-lait macules in Asian patients. J Cosmet Dermatol. 2018; 17 (3): 380-384.
[15]	Hur H, Kim JH, Park IJ, Park CH, Shim DT, et al. The New Treatment of Café Au Lait Spot Using Dr. Hoon Hur’s Golden Parameter Therapy With a High Fluence 1064nm Q-Switched Nd: YAG Laser. 2018; Int J Cur Res. April: 10 (4): 68082-668086.
[16]	Hur H, Shim DT, Song SE, Kim PS, Hyun DN, Kim YR. The Treatment of Infantile Café Au Lait Spot Using Dr. Hoon Hur’s Golden Parameter Therapy with a High Fluence 1064nm Q-Switched Nd: YAG Laser. J Clin Res Dermatol. 2 020; 7 (1): 1-5.
[17]	Hur H, Choi YJ, Cheon MS, Kim YR. The New Treatment of Partial Unilateral Lentiginosis Using Dr. Hoon Hur’s Golden Parameter Therapy With a High Fluence 1064nm Q-Switched Nd: YAG Laser Without Side Effects. Int J Cur Res. 2017; Decem: 9 (12): 63456-63460.
[18]	Hur H, Park CH, Kim YR, Hyun DN. Treatment of Ota’s Nevus Using Dr. Hoon Hur’s Golden Parameter with a High Fluence 1064nm Nd: YAG Laser without Side Effects. J Dermatol Res and Ther. 2017; 3: 1-4.
[19]	Hur H, Kim YR. The Treatment of Hori’s Nevus by New Combination Treatment without Side Effects: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. Hoon Hur’s Optimal Melanocytic Suicide-2 Parameter Therapy. J Clin Res Dermatol. 2017; 4: 1-5.
[20]	Hur H, Park CH, Kim YR, Kim PS. Treatment of a Congenital Melanocytic Nevus by New Combination Therapy: Intense Pulse Light Therapy and Dr. Hoon Hur’s Golden Parameter Therapy. J Dermatol Ther. 2017; 1: 12-16.
[21]	Hur H, Lee GH, Kim PS, Hyun DN, Kim YR. The Treatment of Riehl’s Melanosis Using Dr. Hoon Hur’s Golden Parameter Therapy With a High Fluence 1064nm Q-Switched Nd: YAG Laser Without Side Effects. Int J Cur Res. 2018; Feb: 10 (2): 65103-65108.
[22]	Hur H, In SI, Cheon MS, Choi YJ, Lee DH, Kim YR. The Treatment of Erythema Ab Igne Using Dr. Hoon Hur’s Golden Parameter Therapy With a High Fluence 1064nm Q-Switched Nd: YAG Laser. Int J Cur Res. 2018; Oct: 10 (10): 74218-74221.
[23]	Hur H, Shim DT, Cheon MS, Kim PS, Hyun DN, Kim YR. The Treatment of Postinflammatoty Hyperpigmentation Due To Prurigo Pigmentosa Using Dr. Hoon Hur’s Golden Parameter Therapy With a High Fluence 1064nm Q-Switched Nd: YAG Laser. Int J Cur Res. 2019; Mar: 11 (3): 2491-2494.

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APA Style

Hoon Hur, Jie Hoon Kim, Duck Taik Shim, Suk Jin Choi, Pyoung Su Kim, et al. (2021). The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. Journal of Surgery, 9(1), 16-21. https://doi.org/10.11648/j.js.20210901.13

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ACS Style

Hoon Hur; Jie Hoon Kim; Duck Taik Shim; Suk Jin Choi; Pyoung Su Kim, et al. The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. J. Surg. 2021, 9(1), 16-21. doi: 10.11648/j.js.20210901.13

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AMA Style

Hoon Hur, Jie Hoon Kim, Duck Taik Shim, Suk Jin Choi, Pyoung Su Kim, et al. The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. J Surg. 2021;9(1):16-21. doi: 10.11648/j.js.20210901.13

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@article{10.11648/j.js.20210901.13,
  author = {Hoon Hur and Jie Hoon Kim and Duck Taik Shim and Suk Jin Choi and Pyoung Su Kim and Yu Ri Kim},
  title = {The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy},
  journal = {Journal of Surgery},
  volume = {9},
  number = {1},
  pages = {16-21},
  doi = {10.11648/j.js.20210901.13},
  url = {https://doi.org/10.11648/j.js.20210901.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20210901.13},
  abstract = {Becker’s nevus, a cutaneous hamartoma, usually occurs as a large, unilateral, hyperpigmented and hypertrichotic patch on the shoulder or upper trunk, which can be present in childhood or adolescence. Becker’s nevus can be treated with traditional laser therapy using various types of lasers including a 532nm potassium titanyl phosphate (KTP) laser, 694nm ruby laser and 755nm alexandrite laser. However, this may cause harmful side effects such as scarring, mottled hypopigmentation, post-inflammatory hyperpigmentation (PIH), purpurae, and crusts. As a result, no standard for the treatment of Becker’s nevus using lasers has been established. Therefore, this study was implemented to investigate the safety and efficacy of treating Becker’s nevus using Dr. Hoon Hur’s Golden Parameter Therapy (GPT) followed by Dr. Hoon Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy (OMS-1 PT) which uses a high fluence 1064nm Q-switched Nd: YAG laser (QSNL). Forty-two Koreans suffering from Becker’s nevus participated in the study and received treatment on a weekly basis for 75-100 sessions using the QSNL according to Dr. Hoon Hur’s GPT then followed by Dr. Hoon Hur’s OMS-1 PT. The parameters for this study were a spot size of 7 mm, a fluence of 2.2 J/cm2 and a pulse rate of 10 Hz using a sliding-stacking technique for a single pass over the Becker’s nevus, followed by Dr. Hoon Hur’s OMS-1 PT using a sliding technique for 5 passes with the QSNL over the Becker’s nevus. Upon completion of the last treatment, all 42 patients with Becker’s nevus were cured, having no side effects, and entirely removing the pigmented lesions. None of the 42 patients reported any recurrences after their follow-ups 6-15 months after the final treatment. As a result of this study, we propose therapy to safely and effectively treat Becker’s nevus using a fusion of Dr. Hoon Hur’s GPT and Dr. Hoon Hur’s OMS-1 PT with a high fluence 1064nm QSNL to avoid any recurrences or harmful side effects.},
 year = {2021}
}

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TY - JOUR
T1 - The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy
AU - Hoon Hur
AU - Jie Hoon Kim
AU - Duck Taik Shim
AU - Suk Jin Choi
AU - Pyoung Su Kim
AU - Yu Ri Kim
Y1 - 2021/01/25
PY - 2021
N1 - https://doi.org/10.11648/j.js.20210901.13
DO - 10.11648/j.js.20210901.13
T2 - Journal of Surgery
JF - Journal of Surgery
JO - Journal of Surgery
SP - 16
EP - 21
PB - Science Publishing Group
SN - 2330-0930
UR - https://doi.org/10.11648/j.js.20210901.13
AB - Becker’s nevus, a cutaneous hamartoma, usually occurs as a large, unilateral, hyperpigmented and hypertrichotic patch on the shoulder or upper trunk, which can be present in childhood or adolescence. Becker’s nevus can be treated with traditional laser therapy using various types of lasers including a 532nm potassium titanyl phosphate (KTP) laser, 694nm ruby laser and 755nm alexandrite laser. However, this may cause harmful side effects such as scarring, mottled hypopigmentation, post-inflammatory hyperpigmentation (PIH), purpurae, and crusts. As a result, no standard for the treatment of Becker’s nevus using lasers has been established. Therefore, this study was implemented to investigate the safety and efficacy of treating Becker’s nevus using Dr. Hoon Hur’s Golden Parameter Therapy (GPT) followed by Dr. Hoon Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy (OMS-1 PT) which uses a high fluence 1064nm Q-switched Nd: YAG laser (QSNL). Forty-two Koreans suffering from Becker’s nevus participated in the study and received treatment on a weekly basis for 75-100 sessions using the QSNL according to Dr. Hoon Hur’s GPT then followed by Dr. Hoon Hur’s OMS-1 PT. The parameters for this study were a spot size of 7 mm, a fluence of 2.2 J/cm2 and a pulse rate of 10 Hz using a sliding-stacking technique for a single pass over the Becker’s nevus, followed by Dr. Hoon Hur’s OMS-1 PT using a sliding technique for 5 passes with the QSNL over the Becker’s nevus. Upon completion of the last treatment, all 42 patients with Becker’s nevus were cured, having no side effects, and entirely removing the pigmented lesions. None of the 42 patients reported any recurrences after their follow-ups 6-15 months after the final treatment. As a result of this study, we propose therapy to safely and effectively treat Becker’s nevus using a fusion of Dr. Hoon Hur’s GPT and Dr. Hoon Hur’s OMS-1 PT with a high fluence 1064nm QSNL to avoid any recurrences or harmful side effects.
VL - 9
IS - 1
ER -

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Author Information

Hoon Hur

Choice Dermatology Clinic, Pyeongchon, Korea
Jie Hoon Kim

Choice Dermatology Clinic, Pyeongchon, Korea
Duck Taik Shim

Choice Dermatology Clinic, Pyeongchon, Korea
Suk Jin Choi

Choice Dermatology Clinic, Pyeongchon, Korea
Pyoung Su Kim

Choice Dermatology Clinic, Pyeongchon, Korea
Yu Ri Kim

Choice Dermatology Clinic, Pyeongchon, Korea

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Plain Text BibTeX RIS

APA Style

Hoon Hur, Jie Hoon Kim, Duck Taik Shim, Suk Jin Choi, Pyoung Su Kim, et al. (2021). The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. Journal of Surgery, 9(1), 16-21. https://doi.org/10.11648/j.js.20210901.13

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ACS Style

Hoon Hur; Jie Hoon Kim; Duck Taik Shim; Suk Jin Choi; Pyoung Su Kim, et al. The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. J. Surg. 2021, 9(1), 16-21. doi: 10.11648/j.js.20210901.13

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AMA Style

Hoon Hur, Jie Hoon Kim, Duck Taik Shim, Suk Jin Choi, Pyoung Su Kim, et al. The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy. J Surg. 2021;9(1):16-21. doi: 10.11648/j.js.20210901.13

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@article{10.11648/j.js.20210901.13,
  author = {Hoon Hur and Jie Hoon Kim and Duck Taik Shim and Suk Jin Choi and Pyoung Su Kim and Yu Ri Kim},
  title = {The Treatment of Becker’s Nevus by Combination Therapy: Dr. Hoon Hur’s Golden Parameter Therapy and Dr. HOON Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy},
  journal = {Journal of Surgery},
  volume = {9},
  number = {1},
  pages = {16-21},
  doi = {10.11648/j.js.20210901.13},
  url = {https://doi.org/10.11648/j.js.20210901.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20210901.13},
  abstract = {Becker’s nevus, a cutaneous hamartoma, usually occurs as a large, unilateral, hyperpigmented and hypertrichotic patch on the shoulder or upper trunk, which can be present in childhood or adolescence. Becker’s nevus can be treated with traditional laser therapy using various types of lasers including a 532nm potassium titanyl phosphate (KTP) laser, 694nm ruby laser and 755nm alexandrite laser. However, this may cause harmful side effects such as scarring, mottled hypopigmentation, post-inflammatory hyperpigmentation (PIH), purpurae, and crusts. As a result, no standard for the treatment of Becker’s nevus using lasers has been established. Therefore, this study was implemented to investigate the safety and efficacy of treating Becker’s nevus using Dr. Hoon Hur’s Golden Parameter Therapy (GPT) followed by Dr. Hoon Hur’s Optimal Melanocytic Suicide-1 Parameter Therapy (OMS-1 PT) which uses a high fluence 1064nm Q-switched Nd: YAG laser (QSNL). Forty-two Koreans suffering from Becker’s nevus participated in the study and received treatment on a weekly basis for 75-100 sessions using the QSNL according to Dr. Hoon Hur’s GPT then followed by Dr. Hoon Hur’s OMS-1 PT. The parameters for this study were a spot size of 7 mm, a fluence of 2.2 J/cm2 and a pulse rate of 10 Hz using a sliding-stacking technique for a single pass over the Becker’s nevus, followed by Dr. Hoon Hur’s OMS-1 PT using a sliding technique for 5 passes with the QSNL over the Becker’s nevus. Upon completion of the last treatment, all 42 patients with Becker’s nevus were cured, having no side effects, and entirely removing the pigmented lesions. None of the 42 patients reported any recurrences after their follow-ups 6-15 months after the final treatment. As a result of this study, we propose therapy to safely and effectively treat Becker’s nevus using a fusion of Dr. Hoon Hur’s GPT and Dr. Hoon Hur’s OMS-1 PT with a high fluence 1064nm QSNL to avoid any recurrences or harmful side effects.},
 year = {2021}
}

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